The error means that Windows has blocked your program from launching due to one of the reasons listed above – Microsoft Defender SmartScreen, Smart App Control, an invalid digital signature, or an administrator policy. Firstly, make sure that you have a valid application from a credible developer and then try to find out why it has been blocked. In case you download an official file, you need to right-click on it, choose Properties, and see if there is an option to unblock the file.